A Sensitive Aβ Oligomer Assay Discriminates Alzheimer's and Aged Control Cerebrospinal Fluid

A hallmark of Alzheimer's disease (AD) brain is the amyloid β (Aβ) plaque, which is comprised of Aβ peptides. Multiple lines of evidence suggest that Aβ oligomers are more toxic than other peptide forms. We sought to develop a robust assay to quantify oligomers from CSF. Antibody 19.3 was compa...

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Bibliografiske detaljer
Udgivet i:	J Neurosci
Main Authors:	Savage, Mary J., Kalinina, Juliya, Wolfe, Abigail, Tugusheva, Katherine, Korn, Rachel, Cash-Mason, Tanesha, Maxwell, Jill W., Hatcher, Nathan G., Haugabook, Sharie J., Wu, Guoxin, Howell, Bonnie J., Renger, John J., Shughrue, Paul J., McCampbell, Alexander
Format:	Artigo
Sprog:	Inglês
Udgivet:	Society for Neuroscience 2014
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6608513/ https://ncbi.nlm.nih.gov/pubmed/24553930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1675-13.2014
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A Sensitive Aβ Oligomer Assay Discriminates Alzheimer's and Aged Control Cerebrospinal Fluid

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