A Sensitive Aβ Oligomer Assay Discriminates Alzheimer's and Aged Control Cerebrospinal Fluid

A hallmark of Alzheimer's disease (AD) brain is the amyloid β (Aβ) plaque, which is comprised of Aβ peptides. Multiple lines of evidence suggest that Aβ oligomers are more toxic than other peptide forms. We sought to develop a robust assay to quantify oligomers from CSF. Antibody 19.3 was compa...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Savage, Mary J., Kalinina, Juliya, Wolfe, Abigail, Tugusheva, Katherine, Korn, Rachel, Cash-Mason, Tanesha, Maxwell, Jill W., Hatcher, Nathan G., Haugabook, Sharie J., Wu, Guoxin, Howell, Bonnie J., Renger, John J., Shughrue, Paul J., McCampbell, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608513/
https://ncbi.nlm.nih.gov/pubmed/24553930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1675-13.2014
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