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Unraveling Mechanisms Underlying Partial Agonism in 5-HT(3)A Receptors
Partial agonists have emerged as attractive therapeutic molecules. 2-Me-5HT and tryptamine have been defined as partial agonists of 5-HT(3) receptors on the basis of macroscopic measurements. Because several mechanisms may limit maximal responses, we took advantage of the high-conductance form of th...
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| Publicado no: | J Neurosci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6608499/ https://ncbi.nlm.nih.gov/pubmed/25505338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1970-14.2014 |
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