Oncogenic Signaling Is Dominant to Cell of Origin and Dictates Astrocytic or Oligodendroglial Tumor Development from Oligodendrocyte Precursor Cells

Stem cells, believed to be the cellular origin of glioma, are able to generate gliomas, according to experimental studies. Here we investigated the potential and circumstances of more differentiated cells to generate glioma development. We and others have shown that oligodendrocyte precursor cells (...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Lindberg, Nanna, Jiang, Yiwen, Xie, Yuan, Bolouri, Hamid, Kastemar, Marianne, Olofsson, Tommie, Holland, Eric C., Uhrbom, Lene
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608431/
https://ncbi.nlm.nih.gov/pubmed/25355217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2977-14.2014
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