Oncogenic Signaling Is Dominant to Cell of Origin and Dictates Astrocytic or Oligodendroglial Tumor Development from Oligodendrocyte Precursor Cells

Stem cells, believed to be the cellular origin of glioma, are able to generate gliomas, according to experimental studies. Here we investigated the potential and circumstances of more differentiated cells to generate glioma development. We and others have shown that oligodendrocyte precursor cells (...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Lindberg, Nanna, Jiang, Yiwen, Xie, Yuan, Bolouri, Hamid, Kastemar, Marianne, Olofsson, Tommie, Holland, Eric C., Uhrbom, Lene
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2014
Fag:
Brief Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608431/
https://ncbi.nlm.nih.gov/pubmed/25355217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2977-14.2014
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