Inhibition of Adenylyl Cyclase Type 5 Prevents l-DOPA-Induced Dyskinesia in an Animal Model of Parkinson's Disease

The dopamine precursor l-3,4-dihydroxyphenylalanine (l-DOPA) is widely used as a therapeutic choice for the treatment of patients with Parkinson's disease. However, the long-term use of l-DOPA leads to the development of debilitating involuntary movements, called l-DOPA-induced dyskinesia (LID)...

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Publicado en:J Neurosci
Autores principales: Park, Hye-Yeon, Kang, Young-Mi, Kang, Young, Park, Tae-Shin, Ryu, Young-Kyoung, Hwang, Jung-Hwan, Kim, Yong-Hoon, Chung, Bong-Hyun, Nam, Ki-Hoan, Kim, Mee-Ree, Lee, Chul-Ho, Han, Pyung-Lim, Kim, Kyoung-Shim
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2014
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608409/
https://ncbi.nlm.nih.gov/pubmed/25164669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0864-14.2014
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