Activity-Dependent Tau Protein Translocation to Excitatory Synapse Is Disrupted by Exposure to Amyloid-Beta Oligomers

Tau is a microtubule-associated protein well known for its stabilization of microtubules in axons. Recently, it has emerged that tau participates in synaptic function as part of the molecular pathway leading to amyloid-beta (Aβ)-driven synaptotoxicity in the context of Alzheimer's disease. Here...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Frandemiche, Marie Lise, De Seranno, Sandrine, Rush, Travis, Borel, Eve, Elie, Auréliane, Arnal, Isabelle, Lanté, Fabien, Buisson, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608293/
https://ncbi.nlm.nih.gov/pubmed/24760868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4261-13.2014
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