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α-Melanocyte Stimulating Hormone Prevents GABAergic Neuronal Loss and Improves Cognitive Function in Alzheimer's Disease

In Alzheimer's disease (AD), appropriate excitatory–inhibitory balance required for memory formation is impaired. Our objective was to elucidate deficits in the inhibitory GABAergic system in the TgCRND8 mouse model of AD to establish a link between GABAergic dysfunction and cognitive function....

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ma, Keran, McLaurin, JoAnne
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608113/
https://ncbi.nlm.nih.gov/pubmed/24828629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5075-13.2014
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