Mincle suppresses Toll‐like receptor 4 activation

Regulation of Toll‐like receptor responses is critical for limiting tissue injury and autoimmunity in both sepsis and sterile inflammation. We found that Mincle, a C‐type lectin receptor, regulates proinflammatory Toll‐like receptor 4 signaling. Specifically, Mincle ligation diminishes Toll‐like rec...

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Publicado en:J Leukoc Biol
Main Authors: Greco, Stephanie H., Mahmood, Syed Kashif, Vahle, Anne‐Kristin, Ochi, Atsuo, Batel, Jennifer, Deutsch, Michael, Barilla, Rocky, Seifert, Lena, Pachter, H. Leon, Daley, Donnele, Torres‐Hernandez, Alejandro, Hundeyin, Mautin, Mani, Vishnu R., Miller, George
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
Assuntos:
Inflammation, Extracellular Mediators, & Effector Molecules
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608084/
https://ncbi.nlm.nih.gov/pubmed/26747838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0515-185R
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