Mincle suppresses Toll‐like receptor 4 activation

Regulation of Toll‐like receptor responses is critical for limiting tissue injury and autoimmunity in both sepsis and sterile inflammation. We found that Mincle, a C‐type lectin receptor, regulates proinflammatory Toll‐like receptor 4 signaling. Specifically, Mincle ligation diminishes Toll‐like rec...

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Dades bibliogràfiques
Publicat a:J Leukoc Biol
Autors principals: Greco, Stephanie H., Mahmood, Syed Kashif, Vahle, Anne‐Kristin, Ochi, Atsuo, Batel, Jennifer, Deutsch, Michael, Barilla, Rocky, Seifert, Lena, Pachter, H. Leon, Daley, Donnele, Torres‐Hernandez, Alejandro, Hundeyin, Mautin, Mani, Vishnu R., Miller, George
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Inflammation, Extracellular Mediators, & Effector Molecules
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608084/
https://ncbi.nlm.nih.gov/pubmed/26747838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0515-185R
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