A Pseudomonas aeruginosa hepta‐acylated lipid A variant associated with cystic fibrosis selectively activates human neutrophils

Pseudomonas aeruginosa (PA) infection in cystic fibrosis (CF) lung disease causes airway neutrophilia and hyperinflammation without effective bacterial clearance. We evaluated the immunostimulatory activities of lipid A, the membrane anchor of LPS, isolated from mutants of PA that synthesize structu...

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Detaylı Bibliyografya
Yayımlandı:J Leukoc Biol
Asıl Yazarlar: SenGupta, Shuvasree, Hittle, Lauren E., Ernst, Robert K., Uriarte, Silvia M., Mitchell, Thomas C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Primary Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608067/
https://ncbi.nlm.nih.gov/pubmed/27538572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4VMA0316-101R
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