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A Pseudomonas aeruginosa hepta‐acylated lipid A variant associated with cystic fibrosis selectively activates human neutrophils

Pseudomonas aeruginosa (PA) infection in cystic fibrosis (CF) lung disease causes airway neutrophilia and hyperinflammation without effective bacterial clearance. We evaluated the immunostimulatory activities of lipid A, the membrane anchor of LPS, isolated from mutants of PA that synthesize structu...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: SenGupta, Shuvasree, Hittle, Lauren E., Ernst, Robert K., Uriarte, Silvia M., Mitchell, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608067/
https://ncbi.nlm.nih.gov/pubmed/27538572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4VMA0316-101R
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