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The Fluctuations of Leukocytes and Circulating Cytokines in Septic Humanized Mice Vary With Outcome

Sepsis remains a major challenge in translational research given its heterogeneous pathophysiology and the lack of specific therapeutics. The use of humanized mouse chimeras with transplanted human hematopoietic cells may improve the clinical relevance of pre-clinical studies. However, knowledge of...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Skirecki, Tomasz, Drechsler, Susanne, Hoser, Grazyna, Jafarmadar, Mohammad, Siennicka, Katarzyna, Pojda, Zygmunt, Kawiak, Jerzy, Osuchowski, Marcin F.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607920/
https://ncbi.nlm.nih.gov/pubmed/31297113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01427
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