The Fluctuations of Leukocytes and Circulating Cytokines in Septic Humanized Mice Vary With Outcome

Sepsis remains a major challenge in translational research given its heterogeneous pathophysiology and the lack of specific therapeutics. The use of humanized mouse chimeras with transplanted human hematopoietic cells may improve the clinical relevance of pre-clinical studies. However, knowledge of...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Skirecki, Tomasz, Drechsler, Susanne, Hoser, Grazyna, Jafarmadar, Mohammad, Siennicka, Katarzyna, Pojda, Zygmunt, Kawiak, Jerzy, Osuchowski, Marcin F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607920/
https://ncbi.nlm.nih.gov/pubmed/31297113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01427
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