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The Fluctuations of Leukocytes and Circulating Cytokines in Septic Humanized Mice Vary With Outcome

Sepsis remains a major challenge in translational research given its heterogeneous pathophysiology and the lack of specific therapeutics. The use of humanized mouse chimeras with transplanted human hematopoietic cells may improve the clinical relevance of pre-clinical studies. However, knowledge of...

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Bibliografski detalji
Izdano u:Front Immunol
Glavni autori: Skirecki, Tomasz, Drechsler, Susanne, Hoser, Grazyna, Jafarmadar, Mohammad, Siennicka, Katarzyna, Pojda, Zygmunt, Kawiak, Jerzy, Osuchowski, Marcin F.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607920/
https://ncbi.nlm.nih.gov/pubmed/31297113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01427
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