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A flow extension tethered particle motion assay for single-molecule proteolysis

Regulated proteolysis of signaling proteins under mechanical tension enables cells to communicate with their environment in a variety of developmental and physiologic contexts. The role of force in inducing proteolytic sensitivity has been explored using magnetic tweezers at the single-molecule leve...

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Publicat a:Biochemistry
Autors principals: Drabek, Andrew A., Loparo, Joseph J., Blacklow, Stephen C.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607913/
https://ncbi.nlm.nih.gov/pubmed/30946563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00106
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