Sacubitril/valsartan reduces serum uric acid concentration, an independent predictor of adverse outcomes in PARADIGM‐HF

AIMS: Elevated serum uric acid concentration (SUA) has been associated with an increased risk of cardiovascular disease, but this may be due to unmeasured confounders. We examined the association between SUA and outcomes as well as the effect of sacubitril/valsartan on SUA in patients with heart fai...

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Vydáno v:Eur J Heart Fail
Hlavní autoři: Mogensen, Ulrik M., Køber, Lars, Jhund, Pardeep S., Desai, Akshay S., Senni, Michele, Kristensen, Søren L., Dukát, Andrej, Chen, Chen‐Huan, Ramires, Felix, Lefkowitz, Martin P., Prescott, Margaret F., Shi, Victor C., Rouleau, Jean L., Solomon, Scott D., Swedberg, Karl, Packer, Milton, McMurray, John J.V.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2017
Témata:
Focus on Clinical Trials
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607477/
https://ncbi.nlm.nih.gov/pubmed/29193563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejhf.1056
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