B-type Natriuretic Peptide During Treatment with Sacubitril/Valsartan: the PARADIGM-HF Trial

BACKGROUND: Natriuretic peptides are substrates of neprilysin; hence B-type natriuretic peptide (BNP) concentrations rise with neprilysin inhibition. Thus, the clinical validity of measuring BNP in sacubitril/valsartan-treated patients has been questioned, and use of N-terminal pro-BNP (NT-proBNP) h...

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Publicado en:J Am Coll Cardiol
Main Authors: Myhre, Peder Langeland, Vaduganathan, Muthiah, Claggett, Brian, Packer, Milton, Desai, Akshay S., Rouleau, Jean L., Zile, Michael R., Swedberg, Karl, Lefkowitz, Martin, Shi, Victor, McMurray, John J.V., Solomon, Scott D.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955687/
https://ncbi.nlm.nih.gov/pubmed/30846338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2019.01.018
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