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Sphingosine kinase-1 predicts overall survival outcomes in non-small cell lung cancer patients treated with carboplatin and navelbine

Sphingosine 1-phosphate (S1P) is a bioactive lipid metabolite associated with cancer cell proliferation, survival, migration and regulation of tumor angiogenesis in various cellular and animal models. Sphingosine kinase-1 (SphK1) and S1P lyase are the main enzymes that respectively control the synth...

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Bibliografiske detaljer
Udgivet i:Oncol Lett
Main Authors: Gachechiladze, Mariam, Tichý, Tomáš, Kolek, Vítězslav, Grygárková, Ivona, Klein, Jiří, Mgebrishvili, Giorgi, Kharaishvili, Gvantsa, Janíková, Mária, Smičková, Petra, Cierna, Lucia, Pitson, Stuart, Maddelein, Marie-Lise, Cuvillier, Olivier, Škarda, Jozef
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607215/
https://ncbi.nlm.nih.gov/pubmed/31423186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10447
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