A comparison of Direct sequencing, Pyrosequencing, High resolution melting analysis, TheraScreen DxS, and the K-ras StripAssay for detecting KRAS mutations in non small cell lung carcinomas

BACKGROUND: It is mandatory to confirm the absence of mutations in the KRAS gene before treating metastatic colorectal cancers with epidermal growth factor receptor inhibitors, and similar regulations are being considered for non-small cell lung carcinomas (NSCLC) and other tumor types. Routine diag...

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Detalhes bibliográficos
Main Authors: Jancik, Sylwia, Drabek, Jiri, Berkovcova, Jitka, Xu, Yong Zhong, Stankova, Marcela, Klein, Jiri, Kolek, Vitezslav, Skarda, Josef, Tichy, Tomas, Grygarkova, Ivona, Radzioch, Danuta, Hajduch, Marian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542008/
https://ncbi.nlm.nih.gov/pubmed/22995035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-31-79
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