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Lentivirus-mediated RNA interference targeting programmed death receptor ligand 1 increases the immunologic anti-tumor effect of dendritic cell vaccination against pancreatic cancer in SCID-hu mice

Programmed death receptor ligand 1 (PD-L1), which belongs to the B7 family, is overexpressed in a variety of human cancer types and serves a crucial role in immune escape by malignant cells. Programmed death receptor 1 (PD-1) is a specific PD-L1 receptor. PD-1/PD-L1 signaling inhibits the antitumor...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Wang, Jin, Sun, Mingbing, Zhu, Xinguo, Zhao, Hua, Mao, Deli, Zhang, Zhe, Zhao, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607057/
https://ncbi.nlm.nih.gov/pubmed/31423221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10426
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