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Programmed death-1 concentration at the immunological synapse is determined by ligand affinity and availability
Despite the importance of programmed death-1 (PD-1) for T cell inhibition, little is known about its intracellular trafficking or requirements for localization to the immunological synapse. Here, we show that in activated T cells, PD-1 is present at the plasma membrane, near the Golgi and in the tra...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2077030/ https://ncbi.nlm.nih.gov/pubmed/17968013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708767104 |
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