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The adaptor protein Nck interacts with Fas ligand: Guiding the death factor to the cytotoxic immunological synapse

The Fas ligand (FasL) is a key death factor of cytotoxic T lymphocytes and natural killer cells. It is stored intracellularly as a transmembrane protein of secretory lysosomes. Upon activation, these vesicles are transported to the cytotoxic immunological synapse (IS), and FasL becomes exposed to th...

詳細記述

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書誌詳細
主要な著者: Lettau, Marcus, Qian, Jing, Linkermann, Andreas, Latreille, Mathieu, Larose, Louise, Kabelitz, Dieter, Janssen, Ottmar
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458672/
https://ncbi.nlm.nih.gov/pubmed/16595635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508562103
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