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Oxaliplatin reverses the GLP-1R-mediated promotion of intrahepatic cholangiocarcinoma by altering FoxO1 signaling

Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver cancer, with a 5-year survival rate of <10%; effective drug treatment for ICC is currently lacking. Glucagon-like peptide-1 receptor (GLP-1R) is upregulated in ICC; however, the functions of GLP-1R in ICC remain unknown...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Chen, Bendong, Zhou, Wenyan, Zhao, Wenchao, Yuan, Peng, Tang, Chaofeng, Wang, Genwang, Leng, Junzhi, Ma, Jinlong, Wang, Xiaowen, Hui, Yongfeng, Wang, Qi
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607039/
https://ncbi.nlm.nih.gov/pubmed/31423269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10497
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