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A tale of two clocks: phosphorylation of NICD by CDKs links cell cycle and segmentation clock
The Notch signaling pathway is tightly controlled via post‐transcriptional regulatory mechanisms that promote or terminate pathway activity. In this issue, Carrieri et al [1] show that phosphorylation of the Notch intracellular domain (NICD) by cyclin‐dependent kinases (CDKs) suppresses Notch activi...
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| Gepubliceerd in: | EMBO Rep |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6607009/ https://ncbi.nlm.nih.gov/pubmed/31267704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948247 |
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