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A tale of two clocks: phosphorylation of NICD by CDKs links cell cycle and segmentation clock

The Notch signaling pathway is tightly controlled via post‐transcriptional regulatory mechanisms that promote or terminate pathway activity. In this issue, Carrieri et al [1] show that phosphorylation of the Notch intracellular domain (NICD) by cyclin‐dependent kinases (CDKs) suppresses Notch activi...

詳細記述

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書誌詳細
出版年:EMBO Rep
主要な著者: Braunreiter, Kara M, Cole, Susan E
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607009/
https://ncbi.nlm.nih.gov/pubmed/31267704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948247
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