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Immunomodulatory Effects of Colistin on Macrophages in Rats by Activating the p38/MAPK Pathway

Objectives: Colistin has been identified in a Caenorhabditis elegans chemical screening as an immunostimulatory agent that activates the conserved p38/PMK-1 pathway and provides protection against pathogens. Here we aimed to extend those findings to a mammalian model and evaluate the immunomodulator...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Wang, Jin, Shao, Weili, Niu, Hui, Yang, Tianli, Wang, Yuning, Cai, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606943/
https://ncbi.nlm.nih.gov/pubmed/31297059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00729
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