A Novel Cre Recombinase-Mediated In Vivo Minicircle DNA (CRIM) Vaccine Provides Partial Protection against Newcastle Disease Virus

Minicircle DNA (mcDNA), which contains only the necessary components for eukaryotic expression and is thus smaller than traditional plasmids, has been designed for application in genetic manipulation. In this study, we constructed a novel plasmid containing both the Cre recombinase under the phospho...

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Detalles Bibliográficos
Publicado en:Appl Environ Microbiol
Main Authors: Jiang, Yanlong, Gao, Xing, Xu, Ke, Wang, Jianzhong, Huang, Haibin, Shi, Chunwei, Yang, Wentao, Kang, Yuanhuan, Curtiss, Roy, Yang, Guilian, Wang, Chunfeng
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
Assuntos:
Genetics and Molecular Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606863/
https://ncbi.nlm.nih.gov/pubmed/31053588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00407-19
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