A Novel Cre Recombinase-Mediated In Vivo Minicircle DNA (CRIM) Vaccine Provides Partial Protection against Newcastle Disease Virus

Minicircle DNA (mcDNA), which contains only the necessary components for eukaryotic expression and is thus smaller than traditional plasmids, has been designed for application in genetic manipulation. In this study, we constructed a novel plasmid containing both the Cre recombinase under the phospho...

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Bibliografiske detaljer
Udgivet i:Appl Environ Microbiol
Main Authors: Jiang, Yanlong, Gao, Xing, Xu, Ke, Wang, Jianzhong, Huang, Haibin, Shi, Chunwei, Yang, Wentao, Kang, Yuanhuan, Curtiss, Roy, Yang, Guilian, Wang, Chunfeng
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Genetics and Molecular Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606863/
https://ncbi.nlm.nih.gov/pubmed/31053588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00407-19
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