Salbutamol modifies the neuromuscular junction in a mouse model of ColQ myasthenic syndrome

The β-adrenergic agonists salbutamol and ephedrine have proven to be effective as therapies for human disorders of the neuromuscular junction, in particular many subsets of congenital myasthenic syndromes. However, the mechanisms underlying this clinical benefit are unknown and improved understandin...

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Publicat a:Hum Mol Genet
Autors principals: McMacken, Grace M, Spendiff, Sally, Whittaker, Roger G, O’Connor, Emily, Howarth, Rachel M, Boczonadi, Veronika, Horvath, Rita, Slater, Clarke R, Lochmüller, Hanns
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
General Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606850/
https://ncbi.nlm.nih.gov/pubmed/31220253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz059
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