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Single-cell RNA-seq variant analysis for exploration of genetic heterogeneity in cancer
Inter- and intra-tumour heterogeneity is caused by genetic and non-genetic factors, leading to severe clinical implications. High-throughput sequencing technologies provide unprecedented tools to analyse DNA and RNA in single cells and explore both genetic heterogeneity and phenotypic variation betw...
Guardat en:
| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6606766/ https://ncbi.nlm.nih.gov/pubmed/31267007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45934-1 |
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