Alpha-1-Antitrypsin Enhances Primary Human Macrophage Immunity Against Non-tuberculous Mycobacteria

Rationale: The association between non-tuberculous mycobacterial lung disease and alpha-1-antitrypsin (AAT) deficiency is likely due, in part, to underlying emphysema or bronchiectasis. But there is increasing evidence that AAT itself enhances host immunity against microbial pathogens and thus defic...

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Pubblicato in:Front Immunol
Autori principali: Bai, Xiyuan, Bai, An, Honda, Jennifer R., Eichstaedt, Charles, Musheyev, Ariel, Feng, Zhihong, Huitt, Gwen, Harbeck, Ronald, Kosmider, Beata, Sandhaus, Robert A., Chan, Edward D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606736/
https://ncbi.nlm.nih.gov/pubmed/31293581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01417
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