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Systematic discovery of conservation states for single-nucleotide annotation of the human genome

Comparative genomics sequence data is an important source of information for interpreting genomes. Genome-wide annotations based on this data have largely focused on univariate scores or binary elements of evolutionary constraint. Here we present a complementary whole genome annotation approach, Con...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Commun Biol
Main Authors: Arneson, Adriana, Ernst, Jason
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606595/
https://ncbi.nlm.nih.gov/pubmed/31286065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0488-1
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