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A specific isoform of Pyd/ZO-1 mediates junctional remodeling and formation of slit diaphragms

The podocyte slit diaphragm (SD), responsible for blood filtration in vertebrates, is a major target of injury in chronic kidney disease. The damage includes severe morphological changes with destabilization of SDs and their replacement by junctional complexes between abnormally broadened foot proce...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Carrasco-Rando, Marta, Prieto-Sánchez, Silvia, Culi, Joaquim, Tutor, Antonio S., Ruiz-Gómez, Mar
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605796/
https://ncbi.nlm.nih.gov/pubmed/31171632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201810171
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