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The exocyst controls lysosome secretion and antigen extraction at the immune synapse of B cells

B lymphocytes capture antigens from the surface of presenting cells by forming an immune synapse. Local secretion of lysosomes, which are guided to the synaptic membrane by centrosome repositioning, can facilitate the extraction of immobilized antigens. However, the molecular basis underlying their...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Sáez, Juan José, Diaz, Jheimmy, Ibañez, Jorge, Bozo, Juan Pablo, Cabrera Reyes, Fernanda, Alamo, Martina, Gobert, François-Xavier, Obino, Dorian, Bono, María Rosa, Lennon-Duménil, Ana-María, Yeaman, Charles, Yuseff, María-Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605794/
https://ncbi.nlm.nih.gov/pubmed/31197029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201811131
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