The exocyst controls lysosome secretion and antigen extraction at the immune synapse of B cells

B lymphocytes capture antigens from the surface of presenting cells by forming an immune synapse. Local secretion of lysosomes, which are guided to the synaptic membrane by centrosome repositioning, can facilitate the extraction of immobilized antigens. However, the molecular basis underlying their...

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Detaylı Bibliyografya
Yayımlandı:J Cell Biol
Asıl Yazarlar: Sáez, Juan José, Diaz, Jheimmy, Ibañez, Jorge, Bozo, Juan Pablo, Cabrera Reyes, Fernanda, Alamo, Martina, Gobert, François-Xavier, Obino, Dorian, Bono, María Rosa, Lennon-Duménil, Ana-María, Yeaman, Charles, Yuseff, María-Isabel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Rockefeller University Press 2019
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605794/
https://ncbi.nlm.nih.gov/pubmed/31197029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201811131
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