The exocyst controls lysosome secretion and antigen extraction at the immune synapse of B cells

B lymphocytes capture antigens from the surface of presenting cells by forming an immune synapse. Local secretion of lysosomes, which are guided to the synaptic membrane by centrosome repositioning, can facilitate the extraction of immobilized antigens. However, the molecular basis underlying their...

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Vydáno v:J Cell Biol
Hlavní autoři: Sáez, Juan José, Diaz, Jheimmy, Ibañez, Jorge, Bozo, Juan Pablo, Cabrera Reyes, Fernanda, Alamo, Martina, Gobert, François-Xavier, Obino, Dorian, Bono, María Rosa, Lennon-Duménil, Ana-María, Yeaman, Charles, Yuseff, María-Isabel
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605794/
https://ncbi.nlm.nih.gov/pubmed/31197029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201811131
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