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Proteasome Dependent Actin Remodeling Facilitates Antigen Extraction at the Immune Synapse of B Cells

Engagement of the B cell receptor (BCR) with surface-tethered antigens leads to the formation of an immune synapse (IS), where cell signaling and antigen uptake are tightly coordinated. Centrosome re-orientation to the immune synapse has emerged as a critical regulatory step to guide the local recru...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ibañez-Vega, Jorge, Del Valle Batalla, Felipe, Saez, Juan José, Soza, Andrea, Yuseff, Maria-Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401660/
https://ncbi.nlm.nih.gov/pubmed/30873155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00225
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