Regulation of axon growth by myosin II–dependent mechanocatalysis of cofilin activity

Serotonin (5-HT) is known to increase the rate of growth cone advance via cofilin-dependent increases in retrograde actin network flow and nonmuscle myosin II activity. We report that myosin II activity is regulated by PKC during 5-HT responses and that PKC activity is necessary for increases in tra...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Zhang, Xiao-Feng, Ajeti, Visar, Tsai, Nicole, Fereydooni, Arash, Burns, William, Murrell, Michael, De La Cruz, Enrique M., Forscher, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605792/
https://ncbi.nlm.nih.gov/pubmed/31123185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201810054
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