Hlf marks the developmental pathway for hematopoietic stem cells but not for erythro-myeloid progenitors

Before the emergence of hematopoietic stem cells (HSCs), lineage-restricted progenitors, such as erythro-myeloid progenitors (EMPs), are detected in the embryo or in pluripotent stem cell cultures in vitro. Although both HSCs and EMPs are derived from hemogenic endothelium, it remains unclear how an...

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Veröffentlicht in:J Exp Med
Hauptverfasser: Yokomizo, Tomomasa, Watanabe, Naoki, Umemoto, Terumasa, Matsuo, Junichi, Harai, Ryota, Kihara, Yoshihiko, Nakamura, Eri, Tada, Norihiro, Sato, Tomohiko, Takaku, Tomoiku, Shimono, Akihiko, Takizawa, Hitoshi, Nakagata, Naomi, Mori, Seiichi, Kurokawa, Mineo, Tenen, Daniel G., Osato, Motomi, Suda, Toshio, Komatsu, Norio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2019
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605751/
https://ncbi.nlm.nih.gov/pubmed/31076455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181399
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