CD81 is a novel immunotherapeutic target for B cell lymphoma

The tetraspanin CD81 was initially discovered by screening mAbs elicited against a human B cell lymphoma for their direct antiproliferative effects. We now show that 5A6, one of the mAbs that target CD81, has therapeutic potential. This antibody inhibits the growth of B cell lymphoma in a xenograft...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Med
Prif Awduron: Vences-Catalán, Felipe, Kuo, Chiung-Chi, Rajapaksa, Ranjani, Duault, Caroline, Andor, Noemi, Czerwinski, Debra K., Levy, Ronald, Levy, Shoshana
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Rockefeller University Press 2019
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605745/
https://ncbi.nlm.nih.gov/pubmed/31123084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190186
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