CD81 is a novel immunotherapeutic target for B cell lymphoma

The tetraspanin CD81 was initially discovered by screening mAbs elicited against a human B cell lymphoma for their direct antiproliferative effects. We now show that 5A6, one of the mAbs that target CD81, has therapeutic potential. This antibody inhibits the growth of B cell lymphoma in a xenograft...

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Vydáno v:J Exp Med
Hlavní autoři: Vences-Catalán, Felipe, Kuo, Chiung-Chi, Rajapaksa, Ranjani, Duault, Caroline, Andor, Noemi, Czerwinski, Debra K., Levy, Ronald, Levy, Shoshana
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605745/
https://ncbi.nlm.nih.gov/pubmed/31123084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190186
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