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Blinatumomab, a bispecific B-cell and T-cell engaging antibody, in the treatment of B-cell malignancies

Blinatumomab (Blincyto, Amgen), a bi-specific antibody, is a first-in-class, targeted immunotherapy agent for treatment of B-cell malignancies with a novel mechanism of action which involves in-vivo engagement of the patient’s T cells with CD19-expressing tumour cells. Clinical trials have demonstra...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Burt, Richard, Warcel, Dana, Fielding, Adele K.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605719/
https://ncbi.nlm.nih.gov/pubmed/30380973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2018.1540828
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