Spiral Ganglion Degeneration and Hearing Loss as a Consequence of Satellite Cell Death in Saposin B-Deficient Mice

Saposin B (Sap B) is an essential activator protein for arylsulfatase A in the hydrolysis of sulfatide, a lipid component of myelin. To study Sap B's role in hearing and balance, a Sap B-deficient (B(−/−)) mouse was evaluated. At both light and electron microscopy (EM) levels, inclusion body ac...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Akil, Omar, Sun, Ying, Vijayakumar, Sarath, Zhang, Wujuan, Ku, Tiffany, Lee, Chi-Kyou, Jones, Sherri, Grabowski, Gregory A., Lustig, Lawrence R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2015
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605599/
https://ncbi.nlm.nih.gov/pubmed/25698761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3920-13.2015
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