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Spiral Ganglion Degeneration and Hearing Loss as a Consequence of Satellite Cell Death in Saposin B-Deficient Mice
Saposin B (Sap B) is an essential activator protein for arylsulfatase A in the hydrolysis of sulfatide, a lipid component of myelin. To study Sap B's role in hearing and balance, a Sap B-deficient (B(−/−)) mouse was evaluated. At both light and electron microscopy (EM) levels, inclusion body ac...
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| Udgivet i: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6605599/ https://ncbi.nlm.nih.gov/pubmed/25698761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3920-13.2015 |
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