ATP Binding to Synaspsin IIa Regulates Usage and Clustering of Vesicles in Terminals of Hippocampal Neurons

Synaptic transmission is expensive in terms of its energy demands and was recently shown to decrease the ATP concentration within presynaptic terminals transiently, an observation that we confirm. We hypothesized that, in addition to being an energy source, ATP may modulate the synapsins directly. S...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Shulman, Yoav, Stavsky, Alexandra, Fedorova, Tatiana, Mikulincer, Dan, Atias, Merav, Radinsky, Igal, Kahn, Joy, Slutsky, Inna, Gitler, Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605539/
https://ncbi.nlm.nih.gov/pubmed/25609616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0944-14.2015
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