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Phosphorylation of Synapsin I by Cyclin-Dependent Kinase-5 Sets the Ratio between the Resting and Recycling Pools of Synaptic Vesicles at Hippocampal Synapses

Cyclin-dependent kinase-5 (Cdk5) was reported to downscale neurotransmission by sequestering synaptic vesicles (SVs) in the release-reluctant resting pool, but the molecular targets mediating this activity remain unknown. Synapsin I (SynI), a major SV phosphoprotein involved in the regulation of SV...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Verstegen, Anne M. J., Tagliatti, Erica, Lignani, Gabriele, Marte, Antonella, Stolero, Tamar, Atias, Merav, Corradi, Anna, Valtorta, Flavia, Gitler, Daniel, Onofri, Franco, Fassio, Anna, Benfenati, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608192/
https://ncbi.nlm.nih.gov/pubmed/24849359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3973-13.2014
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