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Lin28B and Let-7 in the Control of Sympathetic Neurogenesis and Neuroblastoma Development
The RNA binding protein Lin28B is expressed in developing tissues and sustains stem and progenitor cell identity as a negative regulator of the Let-7 family of microRNAs, which induces differentiation. Lin28B is activated in neuroblastoma (NB), a childhood tumor in sympathetic ganglia and adrenal me...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6605513/ https://ncbi.nlm.nih.gov/pubmed/26674877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2560-15.2015 |
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