Mouse Model of Chromosome 15q13.3 Microdeletion Syndrome Demonstrates Features Related to Autism Spectrum Disorder

The chromosome 15q13.3 microdeletion is a pathogenic copy number variation conferring epilepsy, intellectual disability, schizophrenia, and autism spectrum disorder (ASD). We generated mice carrying a deletion of 1.2 Mb homologous to the 15q13.3 microdeletion in human patients. Here, we report that...

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Udgivet i:J Neurosci
Main Authors: Kogan, Jeffrey H., Gross, Adam K., Featherstone, Robert E., Shin, Rick, Chen, Qian, Heusner, Carrie L., Adachi, Megumi, Lin, Amy, Walton, Noah M., Miyoshi, Sosuke, Miyake, Shinichi, Tajinda, Katsunori, Ito, Hiroyuki, Siegel, Steven J., Matsumoto, Mitsuyuki
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605504/
https://ncbi.nlm.nih.gov/pubmed/26658876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3967-14.2015
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