Mouse Model of Chromosome 15q13.3 Microdeletion Syndrome Demonstrates Features Related to Autism Spectrum Disorder

The chromosome 15q13.3 microdeletion is a pathogenic copy number variation conferring epilepsy, intellectual disability, schizophrenia, and autism spectrum disorder (ASD). We generated mice carrying a deletion of 1.2 Mb homologous to the 15q13.3 microdeletion in human patients. Here, we report that...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Kogan, Jeffrey H., Gross, Adam K., Featherstone, Robert E., Shin, Rick, Chen, Qian, Heusner, Carrie L., Adachi, Megumi, Lin, Amy, Walton, Noah M., Miyoshi, Sosuke, Miyake, Shinichi, Tajinda, Katsunori, Ito, Hiroyuki, Siegel, Steven J., Matsumoto, Mitsuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605504/
https://ncbi.nlm.nih.gov/pubmed/26658876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3967-14.2015
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