The APP Intracellular Domain Is Required for Normal Synaptic Morphology, Synaptic Plasticity, and Hippocampus-Dependent Behavior

The amyloid precursor protein family (APP/APLPs) has essential roles for neuromuscular synapse development and for the formation and plasticity of synapses within the CNS. Despite this, it has remained unclear whether APP mediates its functions primarily as a cell surface adhesion and signaling mole...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Klevanski, Maja, Herrmann, Ulrike, Weyer, Sascha W., Fol, Romain, Cartier, Nathalie, Wolfer, David P., Caldwell, John H., Korte, Martin, Müller, Ulrike C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605503/
https://ncbi.nlm.nih.gov/pubmed/26658856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2009-15.2015
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