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Expression of ESR1 in Glutamatergic and GABAergic Neurons Is Essential for Normal Puberty Onset, Estrogen Feedback, and Fertility in Female Mice

Circulating estradiol exerts a profound influence on the activity of the gonadotropin-releasing hormone (GnRH) neuronal network controlling fertility. Using genetic strategies enabling neuron-specific deletion of estrogen receptor α (Esr1), we examine here whether estradiol-modulated GABA and glutam...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Cheong, Rachel Y., Czieselsky, Katja, Porteous, Robert, Herbison, Allan E.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605465/
https://ncbi.nlm.nih.gov/pubmed/26511244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1776-15.2015
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