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Complexin Stabilizes Newly Primed Synaptic Vesicles and Prevents Their Premature Fusion at the Mouse Calyx of Held Synapse

Complexins (Cplxs) are small synaptic proteins that cooperate with SNARE-complexes in the control of synaptic vesicle (SV) fusion. Studies involving genetic mutation, knock-down, or knock-out indicated two key functions of Cplx that are not mutually exclusive but cannot easily be reconciled, one in...

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Опубликовано в: :J Neurosci
Главные авторы: Chang, Shuwen, Reim, Kerstin, Pedersen, Meike, Neher, Erwin, Brose, Nils, Taschenberger, Holger
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605347/
https://ncbi.nlm.nih.gov/pubmed/26019341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4841-14.2015
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