Neuronal Pentraxin 1 Negatively Regulates Excitatory Synapse Density and Synaptic Plasticity

In mature neurons, the number of synapses is determined by a neuronal activity-dependent dynamic equilibrium between positive and negative regulatory factors. We hypothesized that neuronal pentraxin (NP1), a proapoptotic protein induced by low neuronal activity, could be a negative regulator of syna...

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Publicado en:J Neurosci
Autores principales: Figueiro-Silva, Joana, Gruart, Agnès, Clayton, Kevin Bernard, Podlesniy, Petar, Abad, Maria Alba, Gasull, Xavier, Delgado-García, José María, Trullas, Ramon
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2015
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605318/
https://ncbi.nlm.nih.gov/pubmed/25855168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2548-14.2015
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